By John S. Bradley MD, John D. Nelson MD Emeritus

ISBN-10: 1581104294

ISBN-13: 9781581104295

This best-selling and ordinary source on pediatric antimicrobial remedy presents immediate entry to trustworthy, up to date options for remedy of all infectious ailments in youngsters. for every sickness, the authors supply a statement to aid healthiness care services choose the simplest of all antimicrobial offerings. Drug descriptions conceal all antimicrobial brokers to be had this day and contain whole information regarding dosing regimens. in keeping with starting to be matters approximately overuse of antibiotics, this system contains guidance on whilst to not prescribe antimicrobials. Key gains: designed if you happen to look after teenagers and are confronted with judgements each day; comprises therapy of parasitic infections and tropical drugs; up-to-date anti-infective drug directory, whole with formulations and dosages; and balanced details on defense, efficacy, and tolerability with facts on expenditures and availability of drugs.

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Extra info for 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy

Example text

B For group B streptococcal meningitis, the recommended dosage for infants ≤7 days of age 200–300 mk/kg/day q8h, and for infants >7 days of age, 300 mg/kg/day q6h. c Azithromycin oral dose for pertussis should be 10 mg/kg once daily for the entire 5-day treatment course, while for other upper respiratory tract infections, 10 mg/kg is given on the first day, followed by 5 mg/kg for 4 subsequent days. For CNS disease, 10 mg/k once daily is recommended for entire course. d Higher dosage may be needed for aspergillus than for candida.

H Zidovudine dosing of 4 mg/kg per dose given PO q12 h has been used for infant prophylaxis in some international perinatal studies. Although there are no definitive data to show equivalent pharmacokinetic parameters or efficacy in preventing transmission, a regimen of ZDV 4 mg/kg per dose given PO twice daily instead of 2 mg/kg per dose given PO 4 times daily may be considered when there are concerns about adherence to drug administration to the infant. i For infants with gestational age <30 wks, change dosing interval to every 8 hours at 4 wks of age.

While maternal treatment with sulfa-containing antibiotics should be approached with caution in the breastfed jaundiced or ill neonate, no symptoms have been associated with maternal treatment with amoxicillin, cefazolin, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, clindamycin, erythromycin, ethambutol, fluconazole, gentamicin, isoniazid, rifampin, (used for <3 weeks). Metronidazole seems safe, but may impart a metallic taste to breast milk. LACT). This Web site provides the Drugs and Lactation Database (LactMed), which contains a peer-reviewed and fully referenced database of drugs to which breastfeeding mothers may be exposed.

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2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy by John S. Bradley MD, John D. Nelson MD Emeritus


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